Yocell Biotechnology (Qingdao) Co., LTD

Since the discovery of liposomes in the 1960s, lipid nanoparticles (LNPs) have evolved into a mainstream drug delivery platform, playing a crucial role especially in COVID-19 mRNA vaccines and nucleic acid therapies, enabling the stable and efficient delivery of therapeutic drugs into cells. To achieve large-scale and high-quality production of LNPs, microfluidic technology is used for the preparation of LNP-mRNA formulations, while tangential flow filtration (TFF) is the core unit operation for subsequent purification, buffer exchange, and impurity removal. We can provide TFF solutions suitable for mRNA-LNP production, covering various filtration forms such as hollow fibers and flat-sheet membrane cassettes, combined with gentle pumps and optimized process parameters, balancing product integrity and production compliance, and supporting the full-process needs from process development to commercial production.

A common challenge in the bioengineering industry is: we have an excellent strain with high expression level, but the performance is far from satisfactory after scale-up cultivation. A practical check of the fermentation process reveal that the wrong type of bioreactor has been selected. This article introduces the characteristics and application scenarios of six common bioreactors to help you determine how to choose a suitable one.

Yocell has successfully won a critical project at a Russian pharmaceutical plant with its YC150-12 Production Homogenizer after intense competition and strict vetting.

The Chief Science Officer of India's DMD Research Center visited Yocell’s TFF manufacturing base for exchanges; Yocell demonstrated its EliteFlow P3 fully automatic TFF system and provided tailored training, which cuts the micro-sample diafiltration time from 14 hours to 2 hours and addresses the client’s core R&D pain point. The experts highly recognized the system and confirmed on-site procurement, with both parties expecting the partnership to boost DMD therapy development and rare disease treatment breakthroughs.

Exosomes, as naturally occurring nanoparticles encapsulated within a phospholipid bilayer and measuring 30–150 nm in diameter, are rapidly emerging as a focal point in biomedical research due to their pivotal roles in intercellular communication, immune regulation, and disease progression.

On January 15, 2026, Yocell’s cutting-edge online webinar goes far beyond showcasing standalone equipment—it will also share optimized processing methodologies for Hansenula yeast in the biopharmaceutical industry, together with tailored equipment selection strategies. Whether you are grappling with R&D bottlenecks or navigating uncertainties during production scale-up, we are committed to delivering targeted solutions to these pain points.