Production Type Tangential Flow Filtration System

The Yocell ProFlow series tangential flow filtration system is specially designed for the concentration of large-scale feed liquids and the replacement of buffer solutions. It adopts tangential flow filtration technology, allowing the liquid to flow parallel to the membrane surface, effectively reducing membrane fouling.

Technique Feature

lThe tangential flow filtration mode is adopted, with the feed liquid flowing parallel to the membrane surface, reducing concentration polarization and contamination clogging on the membrane surface.

lCombining an optimized flow channel design with high shear force technology, the long-term operational flux attenuation rate is low, and the processing volume per unit time meets the demands of large-scale production.

lIt has the functions of continuous operation and automatic control. It can integrate PLC control system to achieve full-process automation of feeding, filtration, cleaning and discharging, reducing the need for manual intervention.

lThe contact material components are made of food-grade / pharmaceutical-grade materials, eliminating the risk of secondary pollution and meeting industry compliance standards such as GMP and FDA.


  • Technical Details
  • URS
  • Download

Main functions

No.

Function

Description

1

Consistant volume

Feeding pump would automatically pump in material, controlled by weighing module on the cycling tank, to maintain a consistant volume, such as for diafiltration

2

Consistant TMP

1. 2 or 3 pressure sensor equiped based on user’s requirements

2. Keep the flow rate, adjust the recycle valve manually or automatically, based on the pressure feeedback. Recommended  method.

3. Or, keep the recycle valve adjustment, change the flow rate according to TMP feedback.

3

Consistant flow rate

Keep the system flow rate by dual feedback from the flow meter at recycle tube and flow through tube.

4

Auto feeding

Automatically supply the material by feeding pump according to weighting modual feedback

5

Weighting

1. Weighting modual available

2. Tank can do the autozero due to connected by soft tubes

6

Temp control

1. Cold water to be supplied by user

2. Temperature automatically controlled by switch on the pump and flow rate of the cold water in the tank jacket, by feedback of the temperature sensor

7

Stirring

Equipped with imported magnetic stirrer at bottom and lower solution level protection/alarm

8

Gas exchange

Equipped with gas filter, 0.22 μm. Optional electric heating function available

9

Sampling

Sampling port and valve available

10

Tank CIP

CIP by spray port, optional pH and Cond probe

11

Water flow through test

Automatically generate the water flow through curve according to date from flow through flow meter

12

Integrity test

Integrity test connecting port availble

13

System CIP

All conponents compliance with CIP. Automatical CIP by programmmed CIP method

14

Software

Programming, monitoring, data analysis

 

Technical parameters

Type

Proflow180

Proflow0800

Proflow1200

Proflow2500

Proflow5000

Proflow10000

Tube size

3/8”

1/2”

3/4”

1”

1-1/2”

2”

Flow rate range

18-180L/h

80-800L/h

120-1200L/h

250-2500L/h

500-5000L/h

1000-10000L///h

Membrane area

0.1-0.5m2

0.5-2m2

0.5-3m2

0.5-5m2

1-10m2

5-20m2

Flow accuracy

Recommended operation flow rate, 10-90% of the maximum value, ±2% accuracy

pH accuracy

Monitor range 2-12. Test accuracy ±0.1. Display ±0.01

Cond accuracy

Standard: range 1μs/cm-300ms/cm, accuracy±3% at 1μs/cm-100ms/cm, accuracy ±5% at 100ms/cm-300ms/cm

Optional: range 0-850ms/cm, accuracy±2% at 0-500ms/cm

Tube material

AIAI 316L, ASME BPE, Ra≤0.38μm, SF4 Polished

Cycling tank

Designed according to URS

Pressure

6Bar

Valve

Air driven diaphragm valve, air supply pressure 5-7bar

Power supply

220VAC 50Hz

220VAC 50Hz

220VAC 50Hz

380VAC 50Hz

380VAC 50Hz

380VAC 50Hz

Power

1.5KW

2.0KW

2.5KW

4.0KW

6.0KW

8.0KW



Brochure

User’s Manual

    Production Type Tangential Flow Filtration System
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