Syn-HL12 High-capacity Nucleic Acid Synthesizer

YCSyn-HL12 High-capacity nucleic acid synthesizer is mainly used for the synthesis of DNA, RNA, special monomers (LNA, dU, dl), and thio-modified nucleic acids, and is suitable for clinical research, pharmaceutical development, and the synthesis of molecular diagnostic probes.

Technical Feature

lThe maximum synthesis scale can reach 15.5mmol.

lThe constant flow pump is made of 316L stainless steel, with a flow rate of up to 200 ml/min. It can withstand organic reagents such as tetrahydrofuran.

lSupport 17-19 types of monomers and 12-14 types of auxiliary reagents.

lThe circulation pump is set up independently to reduce the risk of contamination in the reagent flow path.

lThe software interface is highly user-friendly and highly automated.

lThe rotary switching valve enables flow path switching, with a small dead volume and low reagent loss.

lOnline UV, conductivity, pH, pressure and flow monitoring ensure the safe and high-quality progress of the synthesis process.

lComply with the relevant regulations of the FDA and USP.

lThe large-scale laminar flow fixed synthesis column ensures thorough mixing of reagents and uniform reactions.


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Technical Parameters

Synthesis scale

10μM-15.5mM

Synthesis efficiency

99%

Monomer reagent

17-19

Auxiliary reagent

12-14

Pump flow rate

200mL/min

Number of pumps

Three pumps are configured, with the recirculation pump set up independently, which reduces the risk of reagent flow path contamination.

Material

Resistant to organic reagents such as tetrahydrofuran.

Monitoring type

UV, conductivity, pH, pressure, flow rate

Power voltage

AC110-220V,50-60Hz

Dimension

820×520×740mm

Weight

64kg

 


User’s Manual

    Syn-HL12 High-capacity Nucleic Acid Synthesizer
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