Antibody-conjugated drugs (ADCs) are novel tumor treatment drugs that possess both precise targeting and efficient killing capabilities. With advantages such as enhanced efficacy and reduced systemic toxicity, they have become a research hotspot. The tangential flow filtration (TFF) technology is widely used in the downstream process of ADC drugs, capable of efficiently removing organic impurities, coupling related impurities, and achieving buffer solution replacement. The ADC recovery rate exceeds 90%. This technology requires optimizing the process by controlling key parameters such as inlet and outlet pressure, flow rate, and pH. The core application lies in antibody concentration and desalination, product purification, and buffer solution replacement of ADC drugs, providing core support for the efficient preparation and stability of ADC drugs. Yocell's tangential flow system, through technological innovation, helps advance anti-tumor treatment towards precision and reliability.
The annual global pharmaceutical industry event "Pharmtech & Ingredients" will be grandly launched in Moscow from November 25th to 28th, 2025. At that time, we will make a stunning appearance with our GMP-level fermenter system.
Monoclonal antibody production relies on the long-term stable culture of mammalian cells such as CHO cells and HEK293 cells, which requires high requirements for sterility, parameter stability and contamination prevention and control of the reactor --- GMP stainless steel reactor adopts 316L medical grade stainless steel tank with mirror polishing and double mechanical sealing.
Yocell insists on providing training support to our partners in different countries every year. We always believe that multi-dimensional interaction with our partners not only deepens product knowledge, but also helps us to accurately grasp the needs of the local market and continuously optimise our product solutions.
In the material processing stage of fields such as food, medicine, and bioengineering, "homogenization" is a key process that determines the quality and functionality of the product. It not only makes the particle size of the material more uniform and enhances its stability but also activates the biological activity of the effective components, endowing the product with higher market value. As the core equipment for achieving efficient homogenization, high-pressure homogenizers, with their outstanding technical performance, are becoming the "sharp weapon" for more and more enterprises to break through production bottlenecks and achieve quality upgrades.
Recently, a meticulously crafted 10-liter bench-top plant cell fermenter completed its final inspection and packaging at our production base, officially shipping to our Russian partner. This delivery not only signifies a solid stride for our fermentation equipment in the international market but also highlights the outstanding competitiveness of “China Intelligent Manufacturing” in the field of biotechnology equipment.
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