Pro-Xylane, scientifically named hydroxypropyl tetrahydropyrantriol, is an anti-aging active ingredient developed by L'Oréal. Derived from beech xylose, it features a small molecular weight and can easily penetrate the dermis.
The efficacy of the anti-aging ingredient "Pro-Xylane"
The core benefits of Pro-Xylane include promoting the synthesis of glycosaminoglycans and collagen, strengthening the dermal-epidermal junction, and delivering long-lasting moisturization and skin repair.
Promote the synthesis of glycosaminoglycans (GAGs): GAGs are present in the extracellular matrix of the skin, where they form a network structure to prevent skin moisture loss and maintain skin elasticity and firmness. As people age, the body's ability to synthesize GAGs declines, leading to sagging skin and wrinkles. Pro-Xylane can stimulate GAGs synthesis, improve skin elasticity and reduce wrinkles.
Promote collagen synthesis: Pro-Xylane can accelerate the production of type IV and type VII collagen by dermal cells, strengthen the dermal-epidermal junction, enable glycosaminoglycans to fill the mesh of type IV collagen, improve skin sagging caused by aging, and thereby reduce wrinkles.
Anti-inflammatory and antioxidant: scavenge free radicals, reduce inflammation caused by ultraviolet rays, accelerate the repair of damaged cells and enhance skin tolerance.
The lipid carrier encapsulation prepared by microfluidization high-pressure homogenization
The lipid carrier encapsulation technology prepared by microfluidization high-pressure homogenization can solve the problems of poor transdermal permeability and low stability of Pro-Xylane. It achieves nanonization, high encapsulation efficiency, excellent transdermal permeability and superior stability, making it a mainstream process for high-end anti-aging cosmetics.
Liposomes are bilayered nano hollow microspheres composed of lipids with hydrophilic and lipophilic structures, which can encapsulate Pro-Xylane inside them. As the structure of liposomes is similar to that of cell membranes, they can more easily bind to and penetrate the stratum corneum of the skin, thereby delivering Pro-Xylane into the deep layers of the skin. This can improve the bioavailability of Pro-Xylane and reduce its loss during delivery. In addition, lipid carriers have a sustained-release effect, enabling Pro-Xylane to be released continuously in the skin, prolonging its action time and lowering irritation. Meanwhile, lipid carriers can also protect Pro-Xylane and enhance its stability.
Microfluidization high-pressure homogenization is a mainstream technology for preparing nano lipid carriers (liposome/nano emulsion). It can increase the encapsulation efficiency of Pro-Xylane to 85%~90%, control the particle size within 50~200 nm, and raise the transdermal rate by approximately 40%, which significantly enhances its stability and skin delivery efficiency.
YOCELL can provide various models and specifications of microfluidization high-pressure homogenizers to meet the process requirements at different stages.
