SCG-P-300 Chromatography system

The SCG-P-300's powerful performance and flexible capabilities are ready for all your needs.


●Monoclonal antibody

●Recombinat protein


●Biochemical drug


●Natural products




Dynamic mixer:5ml mixing chamber

Variety of UV detector module options. External fiber optic flow cell.

Conductivity detector:0-999.99mS/cm, temperature compensation possible.


Technical Features

• SCG-P-30 can satisfy milligram level purification need; SCG-P-100 can satisfy gram level purification need; SCG-P-300 can satisfy further scale up needs.

• Carefully designed flow path to minimize the dead volume.

• More add-on expandability available for external valves or future upgrades.

• Powerful SCG operation software offer intuitive and flexible method editor, system controller and data analysis tool. Please note that the software is free for upgrade during the product lifetime.

• Can work with various brand columns from domestic or international vendors.

• Can fit in regular chromatography refrigerator.

• Flexible flow path add-on and sample pump add-on available.

 • Sample pump add-on available.

  • Technical Details
  • URS
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System pump

Imported two duo plunger pump, bioinert PEEK material, provides stable while precise flow rates

Flow rate range

0.01-300 ml/min

System pressure rate

0-6.8 MPa(68bar, 1000psi)


5ml in-line mixer

Flow rate accuracy


Flow rate precision


Supported elution

Isocratic/ramp/step gradient, in-process modification available

UV detector

Option1)Default 260 & 280 nm imported detector, detecting both channels simultaneously. Wavelengths customizable when ordering, including 2.0mm external circulation pool

Option2)200 - 400 nm imported detector, detecting both channels simultaneously, including 2.0mm external flow cell

Option3)200 - 400 nm imported detector, detecting four channels simultaneously, including 2.0mm external flow cell

Option4)200 - 600 nm imported detector, detecting four channels simultaneously, including 2.0mm external circulation pool

Option5)190 - 840 nm imported detector, detecting four channels simultaneously, including 2.0mm external circulation pool

Wavelength precision/repeatability

±1nm / ±0.5nm

UV noise / drift

0.16 mAu(1s)/ 1 mAu/h

Conductivity sensor

0.001-999.99 mS/cm, precision ±0.1 mS/cm or ±2%

Temperature sensor

0-100℃, precision±1℃, can compensate conductivity/pH result automatically

pH sensor

0 - 14, precision ±0.1 (2-12)

In-line bubble detector

Control operation flow via detecting air bubbles in the pipeline

Refractive index detector

Flow rate range: 1-50 ml/min, flow cell volume: 8 μL, assay range: 2.5- 5120 μRIU

Multi-channel mobile phase selection module

A/B pumps available in 1 or 6 Buffer each

Automatic sample injection valve

Software control, automatically injection while switching between Load/Inject/Waste mode

Sample pump

0.1 – 300 ml/min

Sample selection valve

Supports 7 sample inlets, one buffer, biocompatible

Column-position valve module

Option1)Column-position B valve:support for Column and ByPass functions

Option2)Column-position C valve: support direct/reverse column and bypass flow path(Pressure resistance:2Mpa)

Option3)3-column selection module:Support at most 3 columns in-line, controlled by software while support bypass.(Pressure resistance:250psi)

Forward and reverse flush valves:3 column valves are required for forward and reverse flushing of the chromatography column.

Pre/post column pressure monitoring module

Check the pre-and post-column pressure

Collection valve

Six-channel bulk collection valve

SCG Chromatography Workstation

Chromatography Workstation Software:in-house designed operation software

Installation toolkit

PEEK / PTFE pipe, installation manual, user manual, pipe joints, column clip, Flow restrictor, precolumn filter, 1 ml quantitative loop, common tools, etc

Solvent tray

The instrument come with a solvent tray on the top, access easy while saving space

Column supports

Can hold 1ml, 5ml, ID: 10mm, 16mm, 26mm, 50mm columns

Component Collector

FC-S2 component collector,including two racks.

Small size, flexible collection methods, can place the same or different specifications of the collection bracket side by side, automatically identify the collection rack.

13mm collection rack:1 x13mm test tube rack, 90 x 5ml test tubes

16mm collection rack:1 x 16mm test tube rack, 60 x 15ml test tubes

28mm collection rack:1 x 28mm test tube rack, 21 x 50ml test tubes

96-well plate collection rack:1×96-well plate collection rack, containing four deep-well 96-well plates

Wireless monitoring modules

Wireless mobile terminal monitoring module

Sample contact material list

PEEK, Stainless Steel, PPS, PTFE

AC input/ power rating


Instrument weight (gross weight)


Dimension (W*H*D)



User’s Manual

    SCG-P-300 Chromatography system
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